The SEQDESIGN Procedure
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Overview
- Getting Started
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Syntax
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DetailsFixed-Sample Clinical TrialsOne-Sided Fixed-Sample Tests in Clinical TrialsTwo-Sided Fixed-Sample Tests in Clinical TrialsGroup Sequential MethodsStatistical Assumptions for Group Sequential DesignsBoundary ScalesBoundary VariablesType I and Type II ErrorsUnified Family MethodsHaybittle-Peto MethodWhitehead MethodsError Spending MethodsAcceptance (beta) BoundaryBoundary Adjustments for Overlapping Lower and Upper beta BoundariesSpecified and Derived ParametersApplicable Boundary KeysSample Size ComputationApplicable One-Sample Tests and Sample Size ComputationApplicable Two-Sample Tests and Sample Size ComputationApplicable Regression Parameter Tests and Sample Size ComputationAspects of Group Sequential DesignsSummary of Methods in Group Sequential DesignsTable OutputODS Table NamesGraphics OutputODS Graphics
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ExamplesCreating Fixed-Sample DesignsCreating a One-Sided O’Brien-Fleming DesignCreating Two-Sided Pocock and O’Brien-Fleming DesignsGenerating Graphics Display for Sequential DesignsCreating Designs Using Haybittle-Peto MethodsCreating Designs with Various Stopping CriteriaCreating Whitehead’s Triangular DesignsCreating a One-Sided Error Spending DesignCreating Designs with Various Number of StagesCreating Two-Sided Error Spending Designs with and without Overlapping Lower and Upper beta BoundariesCreating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject H0Creating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject or Accept H0Creating a Design with a Nonbinding Beta BoundaryComputing Sample Size for Survival Data That Have Uniform AccrualComputing Sample Size for Survival Data with Truncated Exponential Accrual
- References
Subsections:
- Fixed-Sample Clinical Trials
- One-Sided Fixed-Sample Tests in Clinical Trials
- Two-Sided Fixed-Sample Tests in Clinical Trials
- Group Sequential Methods
- Statistical Assumptions for Group Sequential Designs
- Boundary Scales
- Boundary Variables
- Type I and Type II Errors
- Unified Family Methods
- Haybittle-Peto Method
- Whitehead Methods
- Error Spending Methods
- Acceptance (
) Boundary - Boundary Adjustments for Overlapping Lower and Upper Boundaries
- Specified and Derived Parameters
- Applicable Boundary Keys
- Sample Size Computation
- Applicable One-Sample Tests and Sample Size Computation
- Applicable Two-Sample Tests and Sample Size Computation
- Applicable Regression Parameter Tests and Sample Size Computation
- Aspects of Group Sequential Designs
- Summary of Methods in Group Sequential Designs
- Table Output
- ODS Table Names
- Graphics Output
- ODS Graphics