The SEQDESIGN Procedure
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Overview
- Getting Started
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Syntax
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DetailsFixed-Sample Clinical TrialsOne-Sided Fixed-Sample Tests in Clinical TrialsTwo-Sided Fixed-Sample Tests in Clinical TrialsGroup Sequential MethodsStatistical Assumptions for Group Sequential DesignsBoundary ScalesBoundary VariablesType I and Type II ErrorsUnified Family MethodsHaybittle-Peto MethodWhitehead MethodsError Spending MethodsAcceptance (beta) BoundaryBoundary Adjustments for Overlapping Lower and Upper beta BoundariesSpecified and Derived ParametersApplicable Boundary KeysSample Size ComputationApplicable One-Sample Tests and Sample Size ComputationApplicable Two-Sample Tests and Sample Size ComputationApplicable Regression Parameter Tests and Sample Size ComputationAspects of Group Sequential DesignsSummary of Methods in Group Sequential DesignsTable OutputODS Table NamesGraphics OutputODS Graphics
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ExamplesCreating Fixed-Sample DesignsCreating a One-Sided O’Brien-Fleming DesignCreating Two-Sided Pocock and O’Brien-Fleming DesignsGenerating Graphics Display for Sequential DesignsCreating Designs Using Haybittle-Peto MethodsCreating Designs with Various Stopping CriteriaCreating Whitehead’s Triangular DesignsCreating a One-Sided Error Spending DesignCreating Designs with Various Number of StagesCreating Two-Sided Error Spending Designs with and without Overlapping Lower and Upper beta BoundariesCreating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject H0Creating a Two-Sided Asymmetric Error Spending Design with Early Stopping to Reject or Accept H0Creating a Design with a Nonbinding Beta BoundaryComputing Sample Size for Survival Data That Have Uniform AccrualComputing Sample Size for Survival Data with Truncated Exponential Accrual
- References
Statistical procedures use ODS Graphics to create graphs as part of their output. ODS Graphics is described in detail in Chapter 21: Statistical Graphics Using ODS.
Before you create graphs, ODS Graphics must be enabled (for example, by specifying the ODS GRAPHICS ON statement). For more information about enabling and disabling ODS Graphics, see the section Enabling and Disabling ODS Graphics in Chapter 21: Statistical Graphics Using ODS.
The overall appearance of graphs is controlled by ODS styles. Styles and other aspects of using ODS Graphics are discussed in the section A Primer on ODS Statistical Graphics in Chapter 21: Statistical Graphics Using ODS.
PROC SEQDESIGN assigns a name to each graph it creates. You can use these names to reference the graphs when using ODS. To request these graphs, ODS Graphics must be enabled and you must specify the options indicated in Table 89.13.
Table 89.13: Graphs Produced by PROC SEQDESIGN
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ODS Graph Name |
Plot Description |
Option |
|---|---|---|
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ASNPlot |
Average sample numbers |
PLOTS=ASN |
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BoundaryPlot |
Detailed boundary values |
PLOTS=BOUNDARY |
|
CombinedBoundaryPlot |
Boundary values |
PLOTS=COMBINEDBOUNDARY |
|
ErrSpendPlot |
Error spending |
PLOTS=ERRSPEND |
|
PowerPlot |
Power curves |
PLOTS=POWER |